Therapeutic Plasma Exchange: What Is It, How Does It Work, & More

Medically reviewed by Next Health Clinical Director, Jessica Brewer

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What is a Therapeutic Plasma Exchange? 

How Does Plasma Exchange Work? 

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Therapeutic Plasma Exchange (TPE) is a medical treatment that involves removing some of a patient's blood and separating the plasma (the liquid part of the blood) from the other components, like red and white blood cells. This plasma is then replaced with a substitute solution (Albumin).

The idea behind TPE is to remove any harmful substances or antibodies that might be in a patient's plasma, such as toxins, autoimmune antibodies, or other harmful proteins. By removing these substances, the body can have a chance to recover or respond better to other treatments.  It’s like an “oil change for your health”.

History of TPE: What Disorder can be Treated with Plasma Exchange? 

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TPE has been used for decades in the treatment of autoimmune diseases, such as lupus or multiple sclerosis, where the immune system attacks healthy cells in the body. It can also be used in the treatment of certain neurological or blood disorders, where harmful proteins or antibodies are affecting the normal functioning of the body.  Recent studies have shown improvement in Alzheimer’s disease and improvement of longevity biomarkers.

Does Plasma Exchange Work? Benefits of TPE

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There are several benefits to using TPE as a treatment option. One of the primary benefits is that it can quickly remove harmful substances from a patient's blood, providing rapid relief from symptoms. TPE can also be used as a long-term treatment option for patients with chronic conditions, helping to manage symptoms and prevent complications.

With TPE, you can expect to:

• Reduce inflammation
• Enhance brain health, mental clarity, and memory
• Support heart health and circulation
• Aid detoxification
• Promote immune function
• Rejuvenate overall health

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What is the Difference Between Plasmapheresis and Therapeutic Plasma Exchange?

The terms plasmapheresis (PP) and plasma exchange (PE) are often used interchangeably, though they actually refer to distinct procedures. Plasmapheresis involves the separation of plasma from blood, achieved through methods like centrifugation or membrane filtration. Once separated, the plasma can undergo various manipulations. In contrast, plasma exchange entails the complete removal of plasma, which is then replaced with a substitute fluid. For the purpose of this discussion, we will use PP/PE to describe the combined procedure.

Therapeutic plasmapheresis, also known as platepheresis or plasma exchange, serves to eliminate harmful substances from the bloodstream. To perform this procedure, a small intravenous catheter is inserted into a vein and connected to a specialized machine via plastic tubing. The machine processes the blood, separating it into its components: red blood cells, white blood cells, and plasma. The plasma is discarded, while the remaining components are mixed with a suitable plasma substitute and reintroduced into the individual's circulation.

Optimizing TPE Results

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For those interested in TPE, our medical experts recommend maximizing the benefits of this service by adding Stem Cells or Exosomes to your treatment. Once harmful substances are removed from your blood with TPE, it is an excellent opportunity to potentially enhance your cellular communication with these rejuvenating services.

Interested in enjoying this incredible cutting-edge service?

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